GAAS Analytical specializes in developing robust analytical methods and providing analytical services that are guaranteed to comply with current regulatory mandates and scientific standards.
GAAS Analytical, the service branch of GAAS Corporation was established in 2008 to capitalize on the extensive instrumental analytical knowledge and experience of one of the founders of GAAS Corporations, Dr. Aniko Solyom. GAAS Analytical is an independent contract testing laboratory of natural products, botanical drugs, phytochemicals and dietary supplements, including raw materials, intermediates and finished products. We provide high quality analytical services, including routine testing, analytical method development & validation and contract research & development, to medium and small businesses and educational institutes.
Our methods are in compliance with accepted national and international standard methods including US Pharmacopoeia (USP), European Pharmacopeia (EP), the Association of Analytical Chemists (AOAC), and the Foods Chemical Codex (FCC). We are also licensed by the DEA to test controlled substances.
GAAS Analytical offers analytical testing according to cGMP regulations for identity and purity using mainly HPLC instrumentation. We routinely participate in the Dietary Supplement Laboratory Quality Assurance Program (DSQAP) established by the National Institute of Standards and Technology (NIST) in 2007 with support from the Office of Dietary Supplements (ODS) at the National Institutes of Health. The DSQAP is an extension of collaborative ongoing efforts among ODS, NIST, USDA, and FDA to improve the tools for evaluating dietary supplements. The DSQAP enables participants to improve the accuracy and precision of their measurements in dietary supplement ingredients and finished products.
Our standard analytical reports include not only the end results, but also supporting documents, such as the analytical method(s) used, calibration curves, actual chromatograms and relevant statistics. The FDA regulation of dietary supplements requires companies to prove that the analytical methods they use are scientifically valid - our report satisfies this requirement. This detailed report is part of our standard service; we don't charge extra fee for it (see a sample report).
The CEO and founder of GAAS, Anikó M. Sólyom has more than 30 years of comprehensive experience in analytical method development and validation, using a wide variety of analytical techniques. Her expertise is in development and validation of analytical methods with particular emphasis on HPLC, LC-MS applications and bioactivity guided preparative separation of complex mixtures and analysis of biological samples and dietary supplements that she gained working on drug development and contract analysis both in academia and industry. In addition to HPLC technique she has significant experience with atomic absorption spectroscopy, inductively coupled plasma emission spectroscopy, photoacoustic spectroscopy, UV-Vis spectroscopy, elemental analysis, mass spectrometry, gas chromatography, GC-MS, LC-MS and NMR. She also has experience conducting absorption, distribution and elimination studies on animals.
Before founding GAAS Corporation, Anikó served as director of the Analytical Core at an NIH funded Botanical Center (Arizona Center for Phytomedicine Research). The Facility focused on quantitation and identification of natural products and dietary supplements, particularly anti-inflammatory compounds from turmeric, ginger and boswellia. She developed methods to analyze these compounds from the plant materials, extracts, commercially available dietary supplements and from different biological matrices.
She also managed analytical laboratories working under GLP conditions. For years she served as the Project Manager at the University of Arizona for the "Studies of Chemical Disposition in Mammals" government contract (NO1-ES-45529, NIH/NIEHS), a multi-million dollar project. She also worked for Oncothyreon/ProlX Pharmaceuticals, a company specializing in cancer drug development, as the Manager of Analytical Services. Her duties included developing and validating new assay methods according to cGLP regulations, to quantify novel cancer drugs in plasma and urine using QQQ LC/MS technique; identifying metabolites of new cancer drugs in plasma and urine using TOF LC/MS technique and calculating pharmacokinetic parameters.
She is an active member of AOAC International; she joined the organization in 2002. Currently she is member of AOAC’s Stakeholder Panel on Dietary Supplements responsible for developing, approving, and implementing standards for high priority dietary ingredients. She has participated in multiple AOAC organized collaborative studies (glucosamine, ginkgo, saw palmetto) in order to validate analytical methods to be used by the dietary supplement industry (see References). She was Horwitz advisor of AOAC until the restructuring the Official Methods of Analysis (OMA) process in January 2008, when the role of method advisors and Horwitz advisors was retired. As a former Horwitz advisor she is familiar with the AOAC Official Methods (OMA) program. For 5 years she has been serving as member of the Presidential Task Force on Dietary Supplements of AOAC, and also served as member of Expert Review Panels of AOAC.
The President and co-founder of GAAS Corporation, George Z. Angeli has extensive experience in engineering management, systems engineering and project management for projects ranging from small to very large.
As Systems Engineering Manager, he is the chief technical leader of a $650M federally funded project, the Large Synoptic Survey Telescope. His responsibilities span the entire project, including all the major subsystems and the whole life cycle of the project from the onset of construction to commissioning and handover to operations. Besides integrating the various technical contributions into an integrated system through interface design and specification, modeling, and simulations, he is also responsible for the technical direction and day-to-day priorities for the Commissioning phase of the project.
Formerly he was Head of Systems Engineering of the Thirty Meter Telescope Observatory, an international partnership between the USA, Canada, Japan, India, and China to build an Extremely Large Optical Telescope (ELT). Before that he was the project manager of a team developing real time, phase shifting interferometers at WYKO. During his professional career he led the design or contributed to the development of numerous optical and electronic instruments.
He is the returning chair of the "Modeling, Systems Engineering, and Project Management for Astronomy" international conference organized by SPIE (Society of Photo-Optical Instrumentation Engineers) in every other year. He is on the Editorial Board of the "Journal of Astronomical Telescopes, Instruments, and Systems"; he has 60+ professional publications.
Gabor Angeli is the Chief Information Officer of GAAS Corporation. He currently manages the GAAS website and associated e-mail accounts, and the GAAS data servers. He also oversees and manages the security of the GAAS internal network. Gabor is a graduate of The University of California, Berkeley and is currently pursuing a Ph.D. in computer science at Stanford University.
GAAS Corporation's facility is located in the "Commerce Plaza" in Tucson, Arizona. However, we service clients throughout North America, including clients from Canada. The laboratory is strategically located near The University of Arizona, with convenient freeway access to I-10. Commerce Plaza is a modern office-industrial park conveniently located near the center of the greater Tucson metropolitan area. Each of the 39 office-warehouse units is 1,200 square feet and has its own office, bathroom and 10' X 10' roll-up door at grade level. Commerce Plaza was built to provide incubator rental space for start-up businesses as well as to provide the flexibility of being able to accommodate long-term tenants. A permanent on-site manager ensures that the property is well maintained.
GAAS Corporation's facility consists of 200 square feet of office, 200 square feet for analytical instrumentation and 800 square feet sample preparation and storage space. The facility is protected with a continuously monitored security system and equipped with features required for the health & safety of our employees. The laboratory was designed and constructed for the efficient production of high quality analytical services.
The laboratory is equipped with an Agilent 1200 series Rapid Resolution HPLC system, including SL binary pump, vacuum degasser, thermostatted autosampler, thermostatted column compartment and diode array detector. All instrumentation and computer components are protected against power spikes and outages by an emergency uninterrupted power backup system.
The laboratory is also equipped with the necessary laboratory equipment: UV-vis spectrophotometer, micro- and analytical balances, Buchi R-200 rotary evaporator, benchtop concentrator, solid phase extraction (SPE) apparatus,, water purification system, furnace oven, temperature controlled water bath, centrifuges, vacuum oven, ultra-low temperature freezer, and common laboratory equipment (hot plates, oven, stirrers, shakers, ultrasonic cleaner, mini centrifuge, pH meter, vacuum pumps, refrigerator) to perform the preparation and analysis of samples.
In addition to GAAS' own facility, the company has access on a fee basis to the services of the University of Arizona.
GAAS maintains certificates for cGMP analysis and analysis of controlled substances. In addition, we make a conscious effort foster trust with transparency, and report our scores on the NIST sponsored Dietary Supplement Laboratory Quality Assurance Program (DSQAP). Additionally Aniko publishes regularly in peer-reviewed journals and conference proceedings, listed under our publications.
GAAS Analytical offers analytical testing according to cGMP regulations; Aniko Solyom completed the training on 21 CFR 58, Good Laboratory Practice for Non-Clinical Laboratory Studies.
GAAS Analytical regularly participates in the NIST established Dietary Supplement Laboratory Quality Assurance Program (DSQAP). This is a program to assess the accuracy of a lab's analysis: samples are sent to the lab, and an evaluation is given on how close the lab's reported results are to the gold standard determined by NIST. GAAS regularly provides analysis within the target and consensus range on these exercises. We make all of our results available here:
We are also licensed by the DEA to test controlled substances.